Hellboy is confronted by Grigori Rasputin and begins to find out what he is doing on Earth and who summoned him there. His purpose will be to command the powers that Rasputin is about to unleash upon the world. Hellboy denies this version of his destiny and refuses to be controlled. Attempting to release the Ogdru Jahad, Rasputin is killed, harpooned through the chest by Abe Sapien under the control of the ghost of Elihu Cavendish.

The demonic paranormal investigator known as Hellboy and his team are sent to Austria when a comet that appears to be a spacecraft marked with a swastika targets the ruins of a Nazi research center.